Aims and Scope

Open Chemistry Journal is an open access online journal which publishes review/mini-review articles, letters, short communications and guest edited thematic issues on novel research in the field of chemistry.

  • Physical Chemistry
  • Quantum Chemistry
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  • Bioorganic Chemistry
  • Inorganic Chemistry
  • Electrochemistry
  • Solid-State Chemistry
  • Biochemistry
  • Biophysical Chemistry
  • Bioinorganic Chemistry
  • Environmental Chemistry
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  • Organic Chemistry
  • Medicinal Chemistry
  • Cluster Chemistry
  • Green Chemistry
  • Stereochemistry
  • Neurochemistry Physical
  • Organic Chemistry
  • Materials Chemistry
  • Theoretical Chemistry
  • Immunochemistry
  • Synthetic Chemistry
  • Polymer Chemistry
  • Analytical Chemistry
  • Atmospheric Chemistry
  • Mathematical Chemistry
  • Organometallic Chemistry
  • Immunohistochemistry

Open Chemistry Journal,a rapid peer reviewed journal, is an important and reliable source of current information on developments in the field. The emphasis will be on publishing quality articles rapidly and freely available worldwide.

Editor's Choice

Principle, Instrumentation, and Applications of UPLC: A Novel Technique of Liquid Chromatography

Gita Chawla, Chanda Ranjan

The key focus of the pharmaceutical or chemical industries is to reduce the cost involved in the development of new drugs and to improve the selectivity, sensitivity, and resolution for their detection. The purpose can now be solved by the separation method called UPLC which is the modified HPLC method comprising high pressure and small sized particles (less than 2 µm) used in the column, so the length of the column decreases leading to time saving and reduction in the consumption of solvent. The underlying principle of UPLC is based on van Deemter statement which describes the connection between linear velocity with plate height. UPLC contributes to the improvement of the three areas: speed, resolution, and sensitivity. This is a new advanced category of the HPLC which has the same basic principle and methodology with improved chromatographic performance. This review is an effort to compile the principle, instrumentation, and applications of UPLC.

May 06, 2016

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