A Facile Synthesis of (Z)-2-((5-(4-fluorobenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl) amino) Substituted Acid Using Microwave Irradiation and Conventional Method



Dattatraya N. Pansare, Devanand B. Shinde*
Department of Chemical Technology, Babasaheb Ambedkar Marathwada University, Aurangabad 431 004, India.


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© Pansare and Shinde; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the (https://creativecommons.org/licenses/by/4.0/legalcode), which permits unrestricted, noncommercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Department of Chemical Technology, Babasaheb Ambedkar Marathwada University, Aurangabad 431 004, India; Tel No.:+91 0240-2403308; Fax No.: +91 0240-2400413; E-mail: dbsdattatraya10@rediffmail.com


Abstract

A new effective approach to the synthesis of some new (Z)-2-((5-(4-fluorobenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)amino) substituted acid 6a-l is reported under microwave irradiation as well as conventional conditions.

Keywords: Amino acids, Knoevenagel condensation, Microwave irradiation, Rhodanine.