Flavonoids from the Fresh Leaves of Kalanchoe tomentosa (Crassulaceae)
Lilis Siti Aisyah1, Yenny Febriany Yun1, Euis Julaeha1, Tati Herlina1, Achmad Zainuddin1, Wawan Hermawan2, Unang Supratman1, *, Hideo Hayashi3
Identifiers and Pagination:Year: 2015
First Page: 36
Last Page: 39
Publisher Id: CHEM-2-36
Article History:Received Date: 28/2/2015
Revision Received Date: 11/8/2015
Acceptance Date: 16/9/2015
Electronic publication date: 13/11/2015
open-access license: This is an open access article licensed under the terms of the (https://creativecommons.org/licenses/by/4.0/legalcode), which permits unrestricted, noncommercial use, distribution and reproduction in any medium, provided the work is properly cited.
Flavonoids compounds such as kaempferol (1), kaempferol-3-O-β-D-glucopyranoside or astragalin (2) and kaempferol-3-O-α-L-rhamnoside or afzelin (3) have been isolated from the fresh leaves of Kalanchoe tomentosa (Crassulaceae). The chemical structure of isolated compounds 1-3 were identified by spectroscopic evidences and comparison with those compound previously reported. Compounds 1-3 showed cytotoxic activity against P-388 murine leukimia cells with IC50 values of 51.8, > 100 and 3.32 µg/mL, respectively.