Principle, Instrumentation, and Applications of UPLC: A Novel Technique of Liquid Chromatography
The key focus of the pharmaceutical or chemical industries is to reduce the cost involved in the development of new drugs and to improve the selectivity, sensitivity, and resolution for their detection.
Synthesis and In-vitro Antifungal Evaluation of 5- Pyrazolones
A series of 4-chloro-3-methyl-N-(substituted phenyl)-5-oxo-4,5-dihydro-1H-pyrazole-1- carbothioamide were synthesized using earmark reaction of thiosemicarbazides and ethyl-2-chloroacetoacetate in DMF.
Synthesis and Evaluation of New 2-Iminothiazolidin-4-one and Thiazolidin-2,4-dione Derivatives as Antimicrobial and Anti-inflammatory Agents
A new series of 2-iminothiazolidin-4-ones and thiazolidin-2,4-diones were designed and synthesized. The target compounds were evaluated for antimicrobial and anti-inflammatory activities, aiming to find a candidate carrying dual activities.
Crystal Structure of the Monoprotonated Tripodal Ligand Tris(2,2- bipyrid-6-yl) Methanol.
The tripodal bipyridine-based ligand tris(2,2-bipyrid-6-yl) methanol (L ) was shown in our previous work to have a strong steric preference for trigonal prismatic co - ordination environments with a series of transition metals.
Design and Synthesis of Some Imidazolyl Derivatives: Photophysical Studies and Application in the Detection of Anions
A fluorescent probe based on dicyanovinylphenanthroimidazole (DCPPI) has been designed and synthesized and its potential application to recognize F- and CN- ions via different channels have been tested in different mediums.
Photochromism in Anils - A Review
This review describes in brief the historical perspective of photochromism and photochromic behaviour of ‘Anils’. This phenomenon among ‘Anils’ is exhibited due to the tautomerism between enol and keto form via six membered hydrogen transfer between the phenolic hydrogen and imine nitrogen and show the phenomenon of solid-state photochromism and thermochromism and photochromism in rigid glassy solutions as well.
Crystal Structure Determination and Molecular Docking Studies of 4- (5-Phenyl Pyrazin-2-Yl)-4h-1,2,4 Triazole-3-Thiol with Focal Adhesion Kinase Inhibitors.
The main objective of the present work is to determine crystal structure of the ligand by x-ray methods and to perform molecular docking studies of the ligand 4- Phenyl -5-Pyrazinyl-3-mercapto 1,2,4 Triazole with protein focal adhesion kinase (FAK) domain using the software, Autodock and pymol.
A Facile Synthesis of (Z)-2-((5-(4-fluorobenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl) amino) Substituted Acid Using Microwave Irradiation and Conventional Method
A new effective approach to the synthesis of some new (Z)-2-((5-(4-fluorobenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)amino) substituted acid 6a-l is reported under microwave irradiation as well as conventional conditions.
Editor's Choice
Principle, Instrumentation, and Applications of UPLC: A Novel Technique of Liquid Chromatography
Gita Chawla, Chanda RanjanMay 06, 2016
Other Post
Synthesis and In-vitro Antifungal Evaluation of 5- Pyrazolones
May 09, 2016
Design and Synthesis of a Multi Cu(II)-porphyrin Array
May 25, 2016
Design and Synthesis of Some Imidazolyl Derivatives: Photophysical Studies and Application in the Detection of Anions
May 25, 2016
Synthesis and Characterization of a Series of 1-Aryl-4-[Aryldiazenyl]-piperazines. Part II1. 1-Aryl-4-(2-Aryl-1-Diazenyl)-piperazines with Fluoro-, chloro-, Methyl-, Cyano- and Acetyl Substituents in The 1-Aryl Group
May 31, 2016
Synthesis and Biological Evaluation of Novel Antihypertensive Compounds
June 30, 2016
Crystal Structure Determination and Molecular Docking Studies of 4- (5-Phenyl Pyrazin-2-Yl)-4h-1,2,4 Triazole-3-Thiol with Focal Adhesion Kinase Inhibitors
September 15, 2016
Piperine and Its Various Physicochemical and Biological Aspects: A Review
December 30, 2016
Most Accessed Articles
Principle, Instrumentation, and Applications of UPLC: A Novel Technique of Liquid Chromatography
Gita Chawla, Chanda Ranjan
May 06, 2016Piperine and Its Various Physicochemical and Biological Aspects: A Review
Bhawna Chopra, Ashwani Kumar Dhingra, Ram Prakash Kapoor, Deo Nandan Prasad
December 30, 2016
Deformation Control and Mass Transfer in the Tunic of Halocynthia roretzi
Yoko Kato
March 26, 2018
Michael Addition of Imidazole to α, β -Unsaturated Carbonyl/Cyano Compound
Seetaram Mohapatra, Nilofar Baral, Nilima Priyadarsini Mishra, Pravati Panda, Sabita Nayak
April 30, 2018
Photochromism in Anils - A Review
M.S.M. Rawat, Sudagar Mal, Pramod Singh
February 27, 2015
Novel (N4) Macrocyclic Metal Complexes: Synthesis, Characterization, Spectral Studies and Anticancer Activity
Hanaa A. El-Boraey, Ohyla A. EL-Gammal
June 29, 2018Design and Synthesis of Some Imidazolyl Derivatives: Photophysical Studies and Application in the Detection of Anions
Mohammad Shahid, Rashid Ali, Syed S. Razi, Priyanka Srivastava, Ramesh C. Gupta, Sushil K. Dwivedi, Arvind Misra
May 25, 2016
A Simple, Cost-effective Synthesis of Industrially Important Long Chain Primary Alcohols
Robert Milofsky, James Hurley, Scott Heston, Nicole Hasling, Elise Naughton, Bruce Stevens
March 23, 2017
The Synthesis of a Novel Anticancer Compound, N-(3,5 Dimethoxyphenyl) Acridin-9-Amine and Evaluation of Its Toxicity
Nur A. Ismail, Abbas A. Salman, Mohd S. M. Yusof, Siti K. C. Soh, Hapipah M. Ali, Rozie Sarip
May 21, 2018Synthesis and Characterization of a Series of 1-Aryl-4-[Aryldiazenyl]-piperazines. Part II1. 1-Aryl-4-(2-Aryl-1-Diazenyl)-piperazines with Fluoro-, chloro-, Methyl-, Cyano- and Acetyl Substituents in The 1-Aryl Group
Karen O’Malley, Keith Vaughan
May 31, 2016Synthesis and Biological Evaluation of Novel Antihypertensive Compounds
Fernanda A. Ronchi, Adriana B. Fernandes, Rosana I. Reis, Lys A. F. Mendes, Luís G. Robello, Paula C. Huber, Patricia T. Baraldi, Ricardo V. Marques, Cláudio M. Costa-Neto, Dulce E. Casarini
June 30, 2016
Crystal Structure of the Monoprotonated Tripodal Ligand Tris(2,2’- bipyrid-6-yl) Methanol
Cuhananthan W. Sathiyajith, James C. Knight, Benson M. Kariuki, Peter G. Edwards, Angelo J. Amoroso
November 27, 2014Crystal Structure Determination and Molecular Docking Studies of 4- (5-Phenyl Pyrazin-2-Yl)-4h-1,2,4 Triazole-3-Thiol with Focal Adhesion Kinase Inhibitors
K.S. Kiran, M.K. Kokila, Guruprasad R, Niranjan M.S
September 15, 2016
Synthesis and Evaluation of New 2-Iminothiazolidin-4-one and Thiazolidin-2,4-dione Derivatives as Antimicrobial and Anti-inflammatory Agents
Waleed A. Bayoumi, Shaymaa H. Abdel-Rhman, Mohamed E. Shaker
December 31, 2014
Flavonoids from the Fresh Leaves of Kalanchoe tomentosa (Crassulaceae)
Lilis Siti Aisyah, Yenny Febriany Yun, Euis Julaeha, Tati Herlina, Achmad Zainuddin, Wawan Hermawan, Unang Supratman, Hideo Hayashi
November 13, 2015
A New Synthetic Method of 1,5-Dimethyl-3-Oxabicyclo[3.1.0] Hexane-2,4-Dione
Youcef Mechehoud, Nadjah Belattar, Samir Benayache, Fadila Benayache, Paul Mosset
June 29, 2018Synthesis and In-vitro Antifungal Evaluation of 5- Pyrazolones
Poonam Gupta, Jitendra K. Gupta
May 09, 2016Design and Synthesis of a Multi Cu(II)-porphyrin Array
Virginia Gómez-Vidales, Andres Borja-Miranda, Sandra Cortez-Maya, Oscar Amelines-Sarria, Margarita Rivera, Marcos Martínez-García
May 25, 2016
A Facile Synthesis of (Z)-2-((5-(4-fluorobenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl) amino) Substituted Acid Using Microwave Irradiation and Conventional Method
Dattatraya N. Pansare, Devanand B. Shinde
December 14, 2015
Synthesis and Characterization of a Series of 1-Aryl-4-[aryldiazenyl]- piperazines. Part I. Isomers of N-(2,3-Dimethylphenyl)-N’-(Aryldiazenyl)- Piperazines
Chenguang Fan, Keith Vaughan
October 30, 2015
